Renal disease and kidney

https://www.mayoclinic.org/diseases-conditions/end-stage-renal-disease/symptoms-causes/syc-20354532 Renal disease and kidney Early in chronic kidney disease, you might have no signs or symptoms. As chronic kidney disease progresses to end-stage renal disease, signs and symptoms might include: • Nausea • Vomiting • Loss of appetite • Fatigue and weakness • Changes in how much you urinate • Chest pain, if fluid builds up around the lining of the heart • Shortness of breath, if fluid builds up in the lungs • Swelling of feet and ankles • High blood pressure (hypertension) that's difficult to control • Headaches • Difficulty sleeping • Decreased mental sharpness • Muscle twitches and cramps • Persistent itching • Metallic taste Signs and symptoms of kidney disease are often nonspecific, meaning they can also be caused by other illnesses. Because your kidneys can make up for lost function, signs and symptoms might not appear until irreversible damage has occurred.